Invitrogen™ RASAL1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518226

Catalog No. PIPA518226

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

Specifications

• Antigen: RASAL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rasal1
• Gene Alias: GAP1 like protein; MRASAL; Ras GTPase-activating-like protein; RAS protein activator like 1; RAS protein activator like 1 (GAP1 like); Rasal; Rasal1; RasGAP-activating-like protein 1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 8437
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95294
• Gene Symbols: Rasal1
• Immunogen: Synthetic peptide sequence (QERGKAALGPLGP) corresponding to the C-terminus amino acids of RASAL1 (aa 792-804).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG