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RASAL1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987033
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50-198-7033 100 μL
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Catalog No. 50-198-7033 Supplier Bioss Supplier No. BS6088R
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Rabbit Polyclonal Antibody

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

Specifications

Antigen RASAL1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Rasal1
Gene Accession No. O95294
Gene Alias GAP1 like protein; MRASAL; Ras GTPase-activating-like protein; RAS protein activator like 1; RAS protein activator like 1 (GAP1 like); Rasal; RASAL1; RasGAP-activating-like protein 1
Gene Symbols Rasal1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RASAL1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8437
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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