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RASD2 Monoclonal Antibody (OTI1G1), TrueMAB™, OriGene
SDP

Catalog No. 501673074
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50-167-3074 100 μL
50-254-1877 30 μL
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Catalog No. 50-167-3074 Supplier OriGene Supplier No. TA501978
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Description

Mouse Monoclonal Antibody

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predomitly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.

Specifications

Antigen RASD2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1G1
Concentration 0.66 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene RASD2
Gene Accession No. Q96D21
Gene Alias MGC:4834, Rhes, TEM2
Gene Symbols RASD2
Host Species Mouse
Immunogen Full length human recombit protein of human RASD2 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23551, 481284
Target Species Canine, Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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