RASD2 Mouse anti-Human, Rat, Clone: OTI1A12, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF502070

Catalog No. 50-166-1009

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predomitly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.

Specifications

• Antigen: RASD2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RASD2
• Gene Alias: MGC:4834, Rhes, TEM2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171099, 23551
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1A12
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P63033, Q96D21
• Gene Symbols: Rasd2
• Immunogen: Full length human recombit protein of human RASD2 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2a