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Invitrogen™ RASD2 Polyclonal Antibody
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Catalog No. PIPA5101234
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100 μL
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PIPA5101234 100 μL
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Catalog No. PIPA5101234 Supplier Invitrogen™ Supplier No. PA5101234
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RASD2.

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASD2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RASD2
Gene Accession No. P63032, P63033, Q96D21
Gene Alias 4930526B11Rik; AU045414; GTP-binding protein Rhes; MGC:4834; Ras homolog enriched in striatum; RASD family member 2; RASD family, member 2; Rasd2; Rhes; SE6C; TEM2; TEM-2; Tumor endothelial marker 2
Gene Symbols RASD2
Host Species Rabbit
Immunogen A synthesized peptide derived from human RASD2(Accession Q96D21), corresponding to amino acid residues K120-E170.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171099, 23551, 75141
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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