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RASD2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987659
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50-198-7659 100 μL
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Catalog No. 50-198-7659 Supplier Bioss Supplier No. BS7006R
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Rabbit Polyclonal Antibody

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.

Specifications

Antigen RASD2
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RASD2
Gene Accession No. Q96D21
Gene Alias 4930526B11Rik; AU045414; GTP-binding protein Rhes; MGC:4834; Ras homolog enriched in striatum; RASD family member 2; RASD family, member 2; Rasd2; Rhes; SE6C; TEM2; TEM-2; Tumor endothelial marker 2
Gene Symbols RASD2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RASD2/Tumor endolial marker 2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23551
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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