Invitrogen™ RASGRF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559803

Catalog No. PIPA559803

Description

Immunogen sequence: RKLSLNIPII TGGKALDLAA LSCNSNGYTS MYSAMSPFSK ATLDTSKLYV SSSFTNKIPD EGDTTPEKPE DPSALSKQSS EVSMREESDI DQNQSDDGDT E Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 55%.

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

Specifications

• Antigen: RASGRF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RASGRF1
• Gene Alias: AI844718; ASPP1; Cdc25; CDC25L; CDC25Mm; Gnrp; GRF1; GRF55; Grfbeta; guanine nucleotide exchange factor; guanine nucleotide-releasing factor 1; guanine nucleotide-releasing factor, 55 kD; guanine nucleotide-releasing protein; H-GRF55; KIAA0771; P140 Ras-GRF; p190; P190-A; p190RhoGEF; PP13187; PPP1R13B; Ras guanine release factor beta; Ras protein specific guanine nucleotide releasing factor 1; RAS protein-specific guanine nucleotide-releasing factor 1; Rasgrf1; ras-GRF1; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific guanine nucleotide-releasing factor, CDC25 homolog; ras-specific nucleotide exchange factor CDC25
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5923
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13972
• Gene Symbols: RASGRF1
• Immunogen: Recombinant protein corresponding to Human RASGRF1. Recombinant protein control fragment (Product #RP-98034).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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