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RASGRF1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501728379 Shop All Proteintech Group Inc Products
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50-172-8379 150 μL
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Catalog No. 50-172-8379 Supplier Proteintech Group Inc Supplier No. 129581AP150UL
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Rabbit Polyclonal Antibody

RASGRF1 encodes a protein that is a guanine nucleotide exchange factor similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

Antigen RASGRF1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RASGRF1
Gene Accession No. P27671, P28818, Q13972
Gene Alias CDC25, CDC25L, GNRP, GRF1, GRF55, H GRF55, PP13187, Ras GRF1, RASGRF1
Gene Symbols RASGRF1
Host Species Rabbit
Immunogen RASGRF1 Fusion Protein Ag4072
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192213, 19417, 5923
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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