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Invitrogen™ RASGRP2 Polyclonal Antibody
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Catalog No. PIPA582534
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100 μL
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PIPA582534 100 μL
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Catalog No. PIPA582534 Supplier Invitrogen™ Supplier No. PA582534
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DDSGKVRDPQ LVRMFLMMHP WYIPSSQLAA KLLHIYQQSR KDNSNSLQVK TCHLVRYWIS AFPAEFDLNP ELAEQIKELK ALLDQEGNRR HSSLIDIDSV PTYKWKRQVT QRNPV Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.

The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASGRP2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RASGRP2
Gene Accession No. Q7LDG7, Q9QUG9
Gene Alias Calcium and DAG-regulated guanine nucleotide exchange factor I; calcium and diacylglycerol-regulated guanine nucleotide exchange factor I; Caldaggef1; CalDAG-GEFI; CDC25L; cdc25-like protein; F25B3.3 kinase like protein; F25B3.3 kinase-like protein; guanine exchange factor MCG7; hCDC25L; MCG7; RAP 1A protein-specific guanine nucleotide exchange factor 1; RAS guanyl nucleotide-releasing protein 2; RAS guanyl releasing protein 2; RAS guanyl releasing protein 2 (calcium and DAG-regulated); RAS guanyl-releasing protein 2; RAS, guanyl releasing protein 2; RAS, guanyl releasing protein 2; RAP 1A protein-specific guanine nucleotide exchange factor 1; CalDAG-GEFI; Rasgrp2
Gene Symbols RASGRP2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RASGRP2. Recombinant protein control fragment (Product #RP-90658).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10235, 19395
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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