Invitrogen™ RASGRP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106371

Catalog No. PIPA5106371

Description

Antibody detects endogenous levels of total RASGRP3.

Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.

Specifications

• Antigen: RASGRP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rasgrp3
• Gene Alias: BC066069; calcium and DAG-regulated guanine nucleotide exchange factor III; calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III; CalDAG-GEFIII; Gm327; GRP3; Guanine nucleotide exchange factor for Rap1; KIAA0846; OTTHUMP00000201245; RAS guanyl releasing protein 3; RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3; RAS, guanyl releasing protein 3; Rasgrp3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25780, 313874
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8IV61
• Gene Symbols: Rasgrp3
• Immunogen: A synthesized peptide derived from human RASGRP3(Accession Q8IV61), corresponding to amino acid residues T361-K411.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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