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Invitrogen™ RASIP1 Polyclonal Antibody
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Catalog No. PIPA5104062
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100 μL
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PIPA5104062 100 μL
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Catalog No. PIPA5104062 Supplier Invitrogen™ Supplier No. PA5104062
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RASIP1.

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASIP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RASIP1
Gene Accession No. Q5U651
Gene Alias 1110025D03Rik; 2610025P08Rik; AI853551; RAIN; Ras interacting protein 1; ras-interacting protein 1; Rasip1
Gene Symbols RASIP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human RASIP1(Accession Q5U651), corresponding to amino acid residues V641-L691.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292912, 54922
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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