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Invitrogen™ RASIP1 Polyclonal Antibody
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Catalog No. PIPA5116841
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100 μL
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PIPA5116841 100 μL
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Catalog No. PIPA5116841 Supplier Invitrogen™ Supplier No. PA5116841
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse skeletal muscle Immunogen sequence: TPEAVSVELR PLMLWMANTT ELLSFVQEKV LEMEKEADQE DPQLCNDLEL CDEAMALLDE VIMCTFQQSV YYLTKTLYST LPALLDSNPF TAGAELPGPG AELGAMPPGL RPTLGVFQAA LELTSQCELH PDLVSQTFGY LFFFSNASLL N.

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASIP1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.04 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene RASIP1
Gene Accession No. Q3U0S6, Q5U651
Gene Alias 1110025D03Rik; 2610025P08Rik; AI853551; RAIN; Ras interacting protein 1; ras-interacting protein 1; Rasip1
Gene Symbols RASIP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 635-785 of human RASIP1 (Q5U651).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292912, 54922, 69903
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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