Invitrogen™ RASIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116841

Catalog No. PIPA5116841

Description

Positive Samples: Mouse skeletal muscle Immunogen sequence: TPEAVSVELR PLMLWMANTT ELLSFVQEKV LEMEKEADQE DPQLCNDLEL CDEAMALLDE VIMCTFQQSV YYLTKTLYST LPALLDSNPF TAGAELPGPG AELGAMPPGL RPTLGVFQAA LELTSQCELH PDLVSQTFGY LFFFSNASLL N.

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Specifications

• Antigen: RASIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RASIP1
• Gene Alias: 1110025D03Rik; 2610025P08Rik; AI853551; RAIN; Ras interacting protein 1; ras-interacting protein 1; Rasip1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 292912, 54922, 69903
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.04 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q3U0S6, Q5U651
• Gene Symbols: RASIP1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 635-785 of human RASIP1 (Q5U651).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG