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Invitrogen™ RASIP1 Polyclonal Antibody
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Catalog No. PIPA5142116
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100 μg
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PIPA5142116 100 μg
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Catalog No. PIPA5142116 Supplier Invitrogen™ Supplier No. PA5142116
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Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASIP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene RASIP1
Gene Accession No. Q5U651
Gene Alias 1110025D03Rik; 2610025P08Rik; AI853551; RAIN; Ras interacting protein 1; ras-interacting protein 1; Rasip1
Gene Symbols RASIP1
Host Species Goat
Immunogen Peptide with sequence CANYRHGPPVATSP (aa 951-963).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54922
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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