RASIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-5190	Proteintech Group Inc 260641AP150UL	150 μL

Description

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Specifications

• Antigen: RASIP1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q3U0S6, Q5U651
• Gene ID (Entrez): 292912, 54922, 69903
• Immunogen: RASIP1 Fusion Protein Ag22036
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: RASIP1

• Concentration: 0.23 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: RAIN, Ras interacting protein 1, RASIP1
• Gene Symbols: RASIP1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody