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RASSF1 Mouse anti-Human, Clone: OTI2B11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF502449

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.Specifications
RASSF1 | |
Monoclonal | |
Unconjugated | |
RASSF1 | |
IGKV1/OR-2, IGKV1OR2-PENDING | |
Mouse | |
Affinity Chromatography | |
RUO | |
11186 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI2B11 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9NS23 | |
RASSF1 | |
Full length human recombit protein of human RASSF1 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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