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Invitrogen™ RASSF1 Polyclonal Antibody
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Catalog No. PIPA5102383
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100 μL
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PIPA5102383 100 μL
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Catalog No. PIPA5102383 Supplier Invitrogen™ Supplier No. PA5102383
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RASSF1.

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASSF1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RASSF1
Gene Accession No. Q99MK9, Q9NS23
Gene Alias 123F protein; 123F2; AA536941; AU044980; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; protein 123F2; Ras association (RalGDS/AF-6) domain family 1; Ras association (RalGDS/AF-6) domain family member 1; Ras association domain family 1; Ras association domain family member 1; ras association domain-containing protein 1; Rassf1; Rassf1A; RASSF1A tumor suppressor; Rassf1B; Rassf1C; RDA32; REH3P21; tumor suppressor protein RDA32; wu:fc17f02; WUGSC:H_LUCA12.5; zgc:112224; zgc:92505; zgc:92505 protein
Gene Symbols RASSF1
Host Species Rabbit
Immunogen A synthesized peptide derived from human RASSF1(Accession Q9NS23), corresponding to amino acid residues G162-K212.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11186, 363140, 56289
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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