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Invitrogen™ RASSF10 Polyclonal Antibody
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Catalog No. PIPA521151
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100 μg
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Catalog No. Quantity
PIPA521151 100 μg
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Catalog No. PIPA521151 Supplier Invitrogen™ Supplier No. PA521151
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human lung tissue lysate. PA5-21151 can be used with blocking peptide PEP-1265.

RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RASSF10
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RASSF10
Gene Accession No. A6NK89
Gene Alias 4632411J06Rik; Ras association (RalGDS/AF-6) domain family (N-terminal) member 10; Ras association domain family member 10; ras association domain-containing protein 10; Rassf10
Gene Symbols RASSF10
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of human RASSF10.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 644943
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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