Invitrogen™ RASSF8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558277

Catalog No. PIPA558277

Description

Immunogen sequence: TEFKQKVLNN CKTTADELKK LIRLQTEKLQ SIEKQLESNE IEIRFWEQKY NSNLEEEIVR LEQKIKRNDV EIEEEEFWEN ELQIE Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.

RASSF8 encodes a member of the Ras-association domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: RASSF8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RASSF8
• Gene Alias: 5133400D11Rik; AA815821; AW123240; C12orf2; Carcinoma-associated protein HOJ-1; carcinoma-associated protein HOJ-1 homolog; EGK_03473; HOJ1; HoJ-1; mHoj-1; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; Ras association (RalGDS/AF-6) domain family 8; Ras association domain family member 8; ras association domain-containing protein 8; RASSF8; RGD1308820
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11228
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NHQ8
• Gene Symbols: RASSF8
• Immunogen: Recombinant protein corresponding to Human RASSF8. Recombinant protein control fragment (Product #RP-102815).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG