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Description
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq
Specifications
Specifications
| Antigen | ABCC12 |
| Applications | Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot |
| Classification | Monoclonal |
| Clone | M9II-3 |
| Conjugate | Unconjugated |
| Description | Rat monoclonal antibody raised against partial recombinant ABCC12. |
| Dilution | Immunohistochemistry (Frozen sections) (1:20) Immunocytochemistry (1:20-1:50) Wstern Blot (1:20-1:50) The optimal working dilution should be determined by the end user. |
| Formulation | In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide) |
| Gene | ABCC12 |
| Gene Alias | MGC27071/MRP9 |
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