Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. MABC573MI

MilliporeSigma™ Rat anti-Bcl-2, Clone: 1D7.2,

Catalog No. MABC573MI Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
MABC573MI 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. MABC573MI Supplier MilliporeSigma™ Supplier No. MABC573
Add to Cart
Add to Cart

Description

Rat Monoclonal Antibody

Specifically detects Bcl-2 clone: 1D7.2 in Mouse samples, and it is validated for Western Blotting

Apoptosis regulator Bcl-2 (UniProt P10417; also known as B-cell leukemia/lymphoma 2) is encoded by the Bcl2 (also known as Bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik) gene (Gene ID 12043) in murine species. Bcl-2 is an anti-apoptotic and the founding member of the Bcl-2 family of proteins that paly either a pro- or anti-apoptotic role in cell death signaling. BCL-2 family members are related by regions of sequence and structural homology. The pro-survival members contain four BCL-2 homology regions (BH1–BH4), whereas the BH3-only members contain only the BH3 amphipathic helix, which mediates their interaction with the groove of multi-domain BCL-2 family members. Human BCL2 gene mutatons are well known causes of many cancers, including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bcl-2
Applications Western Blot
Classification Monoclonal
Clone 1D7.2
Formulation Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. P10417
Gene Symbols Bcl2; Bcl-2
Host Species Rat
Immunogen GST-tagged recombinant protein corresponding to the N-terminal of mouse Bcl-2.
Purification Method Protein G Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer
Primary or Secondary Primary
Gene ID (Entrez) NP_033871
Target Species Mouse
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Form Purified
Isotype IgG2a κ
Show More Show Less

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.