CASP2, Rat, Clone: 11B4, Abnova™

Catalog No.	Quantity
89-111-440	100 μg

Catalog No. 89-111-440 Supplier Abnova Corporation Supplier No. MAB3485

Description

Rat monoclonal antibody raised against partial recombinant CASP2.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq

Specifications

• Antigen: CASP2
• Applications: Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 11B4
• Conjugate: Unconjugated
• Description: Rat monoclonal antibody raised against partial recombinant CASP2.
• Dilution: Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: CASP2
• Gene Alias: CASP-2/ICH-1L/ICH-1L/1S/ICH1/NEDD2
• Gene Symbols: CASP2
• Host Species: Rat
• Immunogen: Recombinant protein corresponding p19 subunit of human CASP2.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 835
• Test Specificity: Recognizes an epitope in the p19 subunit of human, mouse, rat, monkey and dog caspase-2. Detects bands of ∼51 KDa (procaspase-2), ∼32 KDa and ∼18 KDa (cleavage products) by Western blot.
• Target Species: Canine, Human, Monkey, Mouse, Rat
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a