CCR5, Rat, Clone: HEK/1/85a, Abnova™

Catalog No.	Quantity
89-111-959	200 μg

Catalog No. 89-111-959 Supplier Abnova Corporation Supplier No. MAB4660

Description

Rat monoclonal antibody raised against native CCR5.

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

• Antigen: CCR5
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: HEK/1/85a
• Conjugate: Unconjugated
• Description: chemokine (C-C motif) receptor 5
• Formulation: In PBS (0.09% sodium azide)
• Gene: CCR5
• Gene Alias: CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
• Gene Symbols: CCR5
• Host Species: Rat
• Immunogen: Native purified CCR5 from CHO cells transfected with human CCR5.
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1234
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2