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Description
The 6A6 monoclonal antibody specifically binds to mouse CD96, which is also known as T cell-activated increased late expression protein (Tactile, TACT). CD96 is a type I transmembrane glycoprotein that belongs to the Ig gene superfamily. It is variably expressed on NK cells , and T cells at all developmental stages, including thymocytes and mature αβ T cells, γδ T cells , and NKT cells. CD96 interacts with Nectin-1 (CD111) and CD155 (poliovirus receptor). CD96 can reportedly mediate adhesive interactions between NK cells or T cells and CD155+ target cells. CD96 may compete with CD226 (DNAM 1) for CD155 binding and thus limit NK cell cytokine responses.
Specifications
Specifications
| Antigen | CD96 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 6A6 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 421 |
| Description | Cd96; T cell-activated increased late expression protein; Tactile; TACT |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse Tactile Recombinant Protein |
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