MilliporeSigma™ Rat anti-CYP11B1, Clone: 80-7,

Catalog No.	Quantity
MABS502MI	100 μg

Catalog No. MABS502MI Supplier MilliporeSigma™ Supplier No. MABS502

Description

Rat Monoclonal Antibody

Specifically detects CYP11B1 clone: 80-7 in Human, Rat samples, and it is validated for Immunohistochemistry, Western Blotting

Cytochrome P450 11B1, mitochondrial (EC1.14.15.4, EC1.14.15.5; UniProt P15538; also known as CYPXIB1, Cytochrome P-450c11, Cytochrome P450C11, Cytochrome P450 subfamily XIB polypeptide 1, Cytochrome P450 XIB1, Steroid 11-beta-monooxygenase, Steroid 11-beta-hydroxylase) is encoded by the CYP11B1 (Also known as CPN1, CYP11B, FHI, P450C11, S11BH) gene in human (Gene ID 1584). CYP11B1 protein is a member of the cytochrome P450 superfamily of monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. It is localized to the inner mitochondrial membrane and mediates the conversion of progesterone to cortisol in the adrenal cortex. CYP11B1 gene mutations are known causes of adrenal hyperplasia 4 (AH4), a form of congenital adrenal hyperplasia due to defective synthesis of cortisol.

Specifications

• Antigen: CYP11B1
• Applications: Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 80-7
• Formulation: Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: P15538
• Gene Symbols: CYP11B1; S11BH
• Host Species: Rat
• Immunogen: Chicken serum albumin-conjugated linear peptide corresponding to human CYP11B1 near the N-terminus.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Signaling
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_000488
• Target Species: Human, Rat
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG2a κ

For Research Use Only