IL-2 Rat anti-Human, APC-R700, Clone: MQ1-17H12, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 565136

Catalog No. BDB565136

Description

The MQ1-17H12 monoclonal antibody specifically binds to the multifunctional cytokine, human Interleukin-2 (IL-2). IL-2 is produced by activated T cells and has multiple functions that can affect the growth, proliferation, differentiation and survival of many different target cell types including T cells, B cells, NK cells, monocytes and macrophages. The immunogen used to generate the MQ1-17H12 hybridoma was purified recombinant human IL-2 protein. The MQ1-17H12 antibody reportedly neutralizes the biological activity of human IL-2.

This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700. APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness. This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).

Specifications

• Antigen: IL-2
• Classification: Monoclonal
• Conjugate: APC-R700
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
• Immunogen: Human IL-2 Recombinant Protein
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: MQ1-17H12
• Description: IL2; Interleukin-2; T-cell growth factor; TCGF
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG2a κ