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IL-2 Rat anti-Human, APC-R700, Clone: MQ1-17H12, BD

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BDB565136 50 Tests
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Catalog No. BDB565136 Supplier BD Biosciences Supplier No. 565136
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Description

Rat Monoclonal Antibody

The MQ1-17H12 monoclonal antibody specifically binds to the multifunctional cytokine, human Interleukin-2 (IL-2). IL-2 is produced by activated T cells and has multiple functions that can affect the growth, proliferation, differentiation and survival of many different target cell types including T cells, B cells, NK cells, monocytes and macrophages. The immunogen used to generate the MQ1-17H12 hybridoma was purified recombinant human IL-2 protein. The MQ1-17H12 antibody reportedly neutralizes the biological activity of human IL-2.

This antibody was conjugated to BD Horizon APC-R700, which has been developed exclusively by BD Biosciences as a better alternative to Alexa Fluor™ 700. APC-R700 excites and emits at similar wavelengths to Alexa Fluor™ 700 yet exhibits significantly improved brightness. This dye can be excited by the red laser and detected with the same filter set as Alexa Fluor™ (eg, 730/45-nm filter).

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-2
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone MQ1-17H12
Conjugate APC-R700
Description IL2; Interleukin-2; T-cell growth factor; TCGF
Formulation Aqueous buffered solution containing BSA, protein stabilizer, glycerol and ≤0.09% sodium azide.
Host Species Rat
Immunogen Human IL-2 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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