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IL10, Rat, Clone: JES3-9D7, Abnova™

Catalog No. 89110697 Shop All Abnova Corporation Products
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89-110-697 1 mg
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Catalog No. 89-110-697 Supplier Abnova Corporation Supplier No. MAB1896
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Description

Rat monoclonal antibody raised against recombinant IL10.

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq

Specifications

Antigen IL10
Applications ELISA, Flow Cytometry, Inhibition Assays
Classification Monoclonal
Clone JES3-9D7
Conjugate Unconjugated
Description interleukin 10
Formulation In PBS, pH 7.2
Gene IL10
Gene Alias CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
Gene Symbols IL10
Host Species Rat
Immunogen Recombinant protein corresponding to human IL10.
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3586
Content And Storage Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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