IL10, Rat, Clone: SPM464, Abnova™

Catalog No.	Quantity
89-111-058	100 μg

Catalog No. 89-111-058 Supplier Abnova Corporation Supplier No. MAB2539

Description

Rat monoclonal antibody raised against synthetic peptide of IL10.

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq

Specifications

• Antigen: IL10
• Applications: ELISA, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: SPM464
• Conjugate: Unconjugated
• Description: Rat monoclonal antibody raised against synthetic peptide of IL10.
• Dilution: Western Blot (0.1-0.2 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In TBS, pH 7.2 (BSA, 10% Proclin300)
• Gene: IL10
• Gene Alias: CSIF/IL-10/IL10A/MGC126450/MGC126451/TGIF
• Gene Symbols: IL10
• Host Species: Rat
• Immunogen: A synthetic peptide corresponding to human IL10.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3586
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Upon initial thawing apportion into working aliquots and store at -80°C for up to six months.
• Form: Liquid