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IL13, Rat, Biotin, Clone: JES10-2E10, Abnova™

Catalog No. 89112505 Shop All Abnova Corporation Products
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500 μg
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89-112-505 500 μg
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Catalog No. 89-112-505 Supplier Abnova Corporation Supplier No. MAB5873
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Description

Rat monoclonal antibody raised against recombinant IL13.

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq

Specifications

Antigen IL13
Applications ELISA
Classification Monoclonal
Clone JES10-2E10
Conjugate Biotin
Description Rat monoclonal antibody raised against recombinant IL13.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene IL13
Gene Alias ALRH/BHR1/IL-13/MGC116786/MGC116788/MGC116789/P600
Gene Symbols IL13
Host Species Rat
Immunogen Recombinant protein corresponding to human IL13.
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3596
Test Specificity human Interleukin-13 (IL-13)1,2. This is a neutralizing antibody.
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1 κ
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