IL4, Rat, Clone: MP4-25D2, Abnova™

Catalog No.	Quantity
89-111-320	500 μg

Catalog No. 89-111-320 Supplier Abnova Corporation Supplier No. MAB3293

Description

Rat monoclonal antibody raised against recombinant IL4.

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq

Specifications

• Antigen: IL4
• Applications: Flow Cytometry, Immunofluorescence
• Classification: Monoclonal
• Clone: MP4-25D2
• Conjugate: Unconjugated
• Description: Rat monoclonal antibody raised against recombinant IL4.
• Dilution: Western Blot (1-5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 100mM BBS, pH 8.2
• Gene: IL4
• Gene Alias: BCGF-1/BCGF1/BSF1/IL-4/MGC79402
• Gene Symbols: IL4
• Host Species: Rat
• Immunogen: Recombinant protein corresponding to human IL4.
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3565
• Test Specificity: human Interleukin-4 (IL-4) The MP4-25D2 antibody has been reported to cross react with IL-4 from Rhesus monkeys. This antibody has also been reported to be useful for epitope mapping of human IL-4.2 This is a neutralizing antibody.
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG1