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Description
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq
Specifications
Specifications
| Antigen | IL7 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | BVD10-11C10 |
| Conjugate | Unconjugated |
| Description | Rat monoclonal antibody raised against recombinant IL7. |
| Dilution | Western Blot (1-5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 100mM BBS, pH 8.2 |
| Gene | IL7 |
| Gene Alias | IL-7 |
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