ITGB4, Rat, Clone: 439-9B, Abnova™

Catalog No.	Quantity
89-109-096	100 μg

Catalog No. 89-109-096 Supplier Abnova Corporation Supplier No. MAB10889

Description

Rat monoclonal antibody raised against ITGB4.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: ITGB4
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 439-9B
• Conjugate: Unconjugated
• Description: Rat monoclonal antibody raised against ITGB4.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In aqueous buffer (0.09% sodium azide)
• Gene: ITGB4
• Gene Alias: CD104
• Gene Symbols: ITGB4
• Host Species: Rat
• Immunogen: Human ITGB4.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3691
• Test Specificity: The monoclonal antibody recognizes human ITGB4, a 202 kDa subunit that associates with integrin alpha 6 (CD49f), thereby forming the laminin receptor. Multiple splice variants have been identified.
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG2b