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MilliporeSigma™ Rat anti-Ly-6G (Azide Free), Clone: 1A8,

Catalog No. MABF839MI Shop All MilliporeSigma Products
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MABF839MI 100 μg
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Catalog No. MABF839MI Supplier MilliporeSigma™ Supplier No. MABF839
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Rat Monoclonal Antibody

Specifically detects Ly-6G (Azide Free) clone: 1A8 in Mouse samples, and it is validated for Activity Assay

The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6G (Azide Free)
Applications Functional Assay
Classification Monoclonal
Clone 1A8
Formulation Purified rat monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Accession No. P35461
Gene Symbols Ly6g
Host Species Rat
Immunogen Propeitary whole cells expressing to mouse Ly-6G.
Purification Method Protein G Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Inflammation and Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Form Purified
Isotype IgG2a κ
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