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CD105 Rat anti-Mouse, Brilliant Violet 510, Clone: MJ7/18, BD Optibuild™

Catalog No. BDB740188 Shop All BD Biosciences Products
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BDB740188 50 μg
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Catalog No. BDB740188 Supplier BD Biosciences Supplier No. 740188
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Description

Rat Monoclonal Antibody

The MJ7/18 monoclonal antibody specifically binds to mouse CD105 (also known as endoglin) which is a homodimer of 90-kDa subunits and is predominantly expressed on vascular endothelial cells. High levels of mouse endoglin mRNA have been reported to be detectable in the ovary, uterus, NCTC-2071 fibroblasts, and to a lesser extent, in heart, muscle and stromal cells in connective tissue of various organs. Endoglin has been reported to play an essential role in embryonic angiogenesis. Both mouse and human endoglin display strong amino-acid sequence homology to the transmembrane and cytoplasmic regions of the type III TGF-ß receptor.

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD105
Applications Flow Cytometry
Classification Monoclonal
Clone MJ7/18
Concentration 0.2mg/mL
Conjugate Brilliant Violet 510
Description Endoglin; Edg; EGLN; Eng; MJ7/18 antigen; S-endoglin
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse skin (inflamed)
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only

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