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CD125 Rat anti-Mouse, Brilliant Violet 786, Clone: T21, BD Optibuild™

Catalog No. BDB741025 Shop All BD Biosciences Products
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BDB741025 50 μg
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Catalog No. BDB741025 Supplier BD Biosciences Supplier No. 741025
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Description

Rat Monoclonal Antibody

The T21 monoclonal antibody specifically binds to CD125 which is also known as the alpha subunit of the IL-5 Receptor (IL5RA/IL-5R α ). CD125 is a type I transmembrane protein that belongs to the hemopoietin receptor and Ig gene superfamilies. It is expressed on B cells and eosinophils. CD125 associates with the Common β chain ( β c/Bc) subunit, also known as CD131, to form the functional IL-5 Receptor complex. Mouse IL-5 belongs to the hematopoietic growth factor family of cytokines and promotes the growth and differentiation of B cells and eosinophils. Upon binding, the T21 antibody blocks IL-5 binding to its receptor and can inhibit IL-5 induced B-cell proliferation and antibody production.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD125
Applications Flow Cytometry
Classification Monoclonal
Clone T21
Concentration 0.2mg/mL
Conjugate Brilliant Violet 786
Description Il5r; Il5ra; IL-5RA; IL-5Rα; IL-5R-alpha; IL-5R subunit alpha
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse T88-M Cell Line
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 λ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only

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