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CD126 Rat anti-Mouse, Brilliant Violet 786, Clone: D7715A7, BD Optibuild™
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The D7715A7 monoclonal antibody specifically binds to the mouse IL-6 receptor, which is also known as, CD126. The immunogen used to generate the D7715A7 hybridoma was OKT4 hybridoma cells. The D7715A7 hybridoma was selected based on its capacity to produce antibody that inhibited IL-6 binding to 2F4 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors). The binding of purified D7715A7 to B9 cells (mouse B-cell hybridoma expressing high levels of IL-6 receptors) is inhibited by recombinant mouse IL-6. This antibody has been reported to inhibit the in vitro and in vivo growth of the IL-6-dependent plasmacytoma line, T1033C2.
Specifications
Specifications
| Antigen | CD126 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | D7715A7 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 786 |
| Description | Il6ra; IL-6 Receptor α chain; IL-6RA; IL-6R alpha |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | OKT4 hybridoma cells |
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Safety and Handling
For Research Use Only
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