CD147 Rat anti-Mouse, Brilliant Violet 510, Clone: RL73 (also known as RL73.2), BD Optibuild™

Catalog No.	Quantity
BDB740191	50 μg

Catalog No. BDB740191 Supplier BD Biosciences Supplier No. 740191

Description

Rat Monoclonal Antibody

The RL73 monoclonal antibody specifically binds to mouse CD147. CD147 is type I membrane glycoprotein and member of the Ig superfamily. CD147 is also known as extracellular matrix metalloproteinase inducer (EMMPRIN) and gp42/basigin (BSG). The CD147 molecule is widely expressed on a variety of hemopoietic and non-hemopoietic cell types including thymocytes, lymphocytes, monocytes, granulocytes, erythroblasts and erythrocytes, endothelial cells and neoplasms. CD147 reportedly plays significant roles in the reproductive, nervous and immune systems and in tumor progression. In the immune system, CD147 can function as an adhesion molecule and signaling receptor that regulates leukocyte trafficking and immune and inflammatory responses.

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.

Specifications

• Antigen: CD147
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: RL73 (also known as RL73.2)
• Concentration: 0.2mg/mL
• Conjugate: Brilliant Violet 510
• Description: Bsg; Basigin; BASI; EMMPRIN; gp 42; HT7; HT-7; Neurothelin
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Rat
• Immunogen: Mouse EL4 Cell Subline
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Mouse
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG2a κ

For Research Use Only