CD153 Rat anti-Mouse, Brilliant Violet 421, Clone: RM153, BD Optibuild™

Catalog No.	Quantity
BDB740059	50 μg

Catalog No. BDB740059 Supplier BD Biosciences Supplier No. 740059

Description

Rat Monoclonal Antibody

The RM153 monoclonal antibody specifically recognizes a 40-kDa type-II membrane glycoprotein, CD30 ligand (CD30L or CD153), which belongs to the NGF/TNF superfamily. In the presence of cytokines, CD153 stimulates B-cell proliferation, antigen-specific antibody production, and polyclonal immunoglobulin secretion. In addition, it costimulates the proliferation of activated T cells. This molecule is expressed on activated T cells, predominantly CD4+, on activated EL4 cells, and on activated Th1 and Th2 cells. The RM153 mAb inhibits the binding of CD153 to CD30.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

• Antigen: CD153
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: RM153
• Concentration: 0.2mg/mL
• Conjugate: Brilliant Violet 421
• Description: CD30 Ligand; Cd30l; CD30LG; Tnfsf8
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Rat
• Immunogen: CHO cells transfected with mouse CD153 gene (Tnfsf8)
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Mouse
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG2b κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only