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CD153 Rat anti-Mouse, Brilliant Violet 421, Clone: RM153, BD Optibuild™

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 740059

Catalog No. BDB740059


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Description

Description

The RM153 monoclonal antibody specifically recognizes a 40-kDa type-II membrane glycoprotein, CD30 ligand (CD30L or CD153), which belongs to the NGF/TNF superfamily. In the presence of cytokines, CD153 stimulates B-cell proliferation, antigen-specific antibody production, and polyclonal immunoglobulin secretion. In addition, it costimulates the proliferation of activated T cells. This molecule is expressed on activated T cells, predominantly CD4+, on activated EL4 cells, and on activated Th1 and Th2 cells. The RM153 mAb inhibits the binding of CD153 to CD30.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

Specifications

CD153
RM153
Brilliant Violet 421
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2b, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
CD30 Ligand; Cd30l; CD30LG; Tnfsf8
Affinity Purified
CHO cells transfected with mouse CD153 gene (Tnfsf8)
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine
Documents
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