CD193 Rat anti-Mouse, Brilliant Violet 650, Clone: 83103, BD Optibuild™

Catalog No.	Quantity
BDB740440	50 μg

Catalog No. BDB740440 Supplier BD Biosciences Supplier No. 740440

Description

Rat Monoclonal Antibody

The 83103 monoclonal antibody specifically binds to CD193, which is also known as, C-C chemokine receptor type 3 (CCR3). CD193 is a chemokine receptor for CCL11/eotaxin, CCL24/eotaxin-2, CCL26/eotaxin-3, CCL5/RANTES, CCL7/MCP-3, CCL8/MCP-2, CCL14/MCP-4, CCL15/HCC-2 and CCL3/MIP-1a. CD193 is reportedly expressed on eosinophils, mast cells and Th2 cells. It plays an important role in eosinophil recruitment to the skin and the lung and in the development of airway hyperresponsiveness.

The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm. BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination.

Specifications

• Antigen: CD193
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: 83103
• Concentration: 0.2mg/mL
• Conjugate: Brilliant Violet 650
• Description: CCR3; CCR-3; chemokine (C-C) receptor 3; CC-CKR3; C-C CKR-3; CKR3; CC-CKR-3
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Rat
• Immunogen: Mouse CCR3 transfected Cells Transfected Cell Line
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Mouse
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG2a

For Research Use Only