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CD196 (CCR6) Rat anti-Mouse, Brilliant Violet 650, Clone: 140706, BD Optibuild™

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 740441

Catalog No. BDB740441


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Description

Description

The 140706 monoclonal antibody specifically binds to mouse CD196 (CCR6), a CC chemokine receptor that is expressed on B lymphocytes and subsets of T and dendritic cells. The known ligand for CCR6 is CCL20/MIP-3 α , and together they regulate the migration and recruitment of antigen-presenting and immunocompetent cells during inflammatory and immunological responses.

The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm. BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination.

Specifications

Specifications

CD196 (CCR6)
140706
Brilliant Violet 650
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2a
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
CCR6, BN-1, CKR-L3, DRY6, KY411, GPR-CY4, STRL22
Affinity Purified
Mouse CCR6-transfected Rat Cell Line
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine
Documents
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