CD196 (CCR6) Rat anti-Mouse, Brilliant Violet 786, Clone: 140706, BD Optibuild™

Rat Monoclonal Antibody

Supplier:  BD Biosciences 740840

Catalog No. BDB740840

Description

The 140706 monoclonal antibody specifically binds to mouse CD196 (CCR6), a CC chemokine receptor that is expressed on B lymphocytes and subsets of T and dendritic cells. The known ligand for CCR6 is CCL20/MIP-3 α , and together they regulate the migration and recruitment of antigen-presenting and immunocompetent cells during inflammatory and immunological responses.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Specifications

• Antigen: CD196 (CCR6)
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: CCR6, BN-1, CKR-L3, DRY6, KY411, GPR-CY4, STRL22
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: 140706
• Conjugate: Brilliant Violet 786
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse CCR6-transfected Rat Cell Line
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only