CD41 Rat anti-Mouse, Brilliant Violet 711, Clone: MWReg30, BD Optibuild™
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 740712
The MWReg30 monoclonal antibody specifically binds to CD41, which is also known as glycoprotein IIb (gpIIb, GP IIb), Integrin α IIb chain, or Integrin alpha 2b. CD41 is a transmembrane glycoprotein that is encoded by Itga2b . CD41 associates with I ntegrin β3 chain (g pIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.
|Brilliant Violet 711|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Itga2b; Integrin alpha 2b; Integrin alpha-IIb; Integrin α IIb; GpIIb|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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