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CD41 Rat anti-Mouse, Brilliant Violet 711, Clone: MWReg30, BD Optibuild™

Catalog No. BDB740712 Shop All BD Biosciences Products
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BDB740712 50 μg
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Catalog No. BDB740712 Supplier BD Biosciences Supplier No. 740712
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Description

Rat Monoclonal Antibody

The MWReg30 monoclonal antibody specifically binds to CD41, which is also known as glycoprotein IIb (gpIIb, GP IIb), Integrin α IIb chain, or Integrin alpha 2b. CD41 is a transmembrane glycoprotein that is encoded by Itga2b . CD41 associates with I ntegrin β3 chain (g pIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD41
Applications Flow Cytometry
Classification Monoclonal
Clone MWReg30
Concentration 0.2mg/mL
Conjugate Brilliant Violet 711
Description Itga2b; Integrin alpha 2b; Integrin alpha-IIb; Integrin α IIb; GpIIb
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse Platelets
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only

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