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CD41 Rat anti-Mouse, Brilliant Violet 786, Clone: MWReg30, BD Optibuild™

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 740903

Catalog No. BDB740903


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Description

Description

The MWReg30 monoclonal antibody specifically binds to CD41, which is also known as glycoprotein IIb (gpIIb, GP IIb), Integrin α IIb chain, or Integrin alpha 2b. CD41 is a transmembrane glycoprotein that is encoded by Itga2b . CD41 associates with I ntegrin β3 chain (g pIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis.

Specifications

Specifications

CD41
MWReg30
Brilliant Violet 786
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Itga2b; Integrin alpha 2b; Integrin alpha-IIb; Integrin α IIb; GpIIb
Affinity Purified
Mouse Platelets
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine
Documents
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