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CD49d Rat anti-Mouse, Brilliant Violet 510, Clone: R1-2, BD Optibuild™

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 740112

Catalog No. BDB740112


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Description

Description

The R1-2 monoclonal antibody specifically binds to α 4 chain (CD49d), which is expressed as a heterdimer with either of two β , β 1 or β 7 (also known as β p). The α 4β α 4β 7 also preferentially binds to the mucosal vascular addressin, MAdCAM-1. The R1-2 antibody blocks some α 4 integrin-mediated binding functions. In combination with mAb 9C10 (MFR4.B) (Cat. No. 553313), binding of VLA-4 expressing cells to VCAM-1 can be almost completely inhibited.

Specifications

Specifications

CD49d
R1-2
Brilliant Violet 510
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
CDF IgG2b, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Integrin α4; Itga4; Integrin alpha-4; LPAM alpha; VLA-4 alpha; VLA-4a
Affinity Purified
AKR/Cum mouse spontaneous T lymphoma line TK1
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine
Documents
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