Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. BDB740931

CD70 Rat anti-Mouse, Brilliant Violet 786, Clone: FR70, BD Optibuild™

Catalog No. BDB740931 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB740931 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. BDB740931 Supplier BD Biosciences Supplier No. 740931
Add to Cart
Add to Cart

Description

Rat Monoclonal Antibody

The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33-kDa type-II transmembrane glycoprotein belonging to the TNF/NGF superfamily. CD70 is the ligand for CD27 and is expressed primarily on activated B cells. CD70 expression can be induced by activation of splenocytes with lipopolysaccharide and stimulatory antibodies specific for IgM, CD40 or both. mRNA coding for CD70 is transiently expressed after Concanavalin A stimulation of splenocytes or thymocytes. CD70 has been observed to be expressed on dendritic cells of Leishmania major -infected mice. The CD27-CD70 interaction delivers costimulatory signals to T cells and NK cells. It has been reported that FR70 antibody blocks binding of mCD27-Ig fusion protein to mouse Cd70 -transfected cells and inhibits some in vitro T-cell- and NK-cell-dependent responses.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD70
Applications Flow Cytometry
Classification Monoclonal
Clone FR70
Concentration 0.2mg/mL
Conjugate Brilliant Violet 786
Description CD27 ligand; CD27l, CD27LG; Tnfsf7; Ki-24 Antigen
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen BALB/c mouse B lymphoma A20.2J
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
Show More Show Less

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.