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LPAM-1 Rat anti-Mouse, Brilliant Violet 711, Clone: DATK32, BD Optibuild™

Catalog No. BDB740701 Shop All BD Biosciences Products
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BDB740701 50 μg
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Catalog No. BDB740701 Supplier BD Biosciences Supplier No. 740701
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Description

Rat Monoclonal Antibody

The DATK32 monoclonal antibody specifically binds to an epitope specific for the α 4β 7 integrin heterodimer. α 4β 7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells. It interacts with several ligands, including VCAM-1 (CD106), fibronectin, and MAdCAM-1. DATK32 antibody induces α 4β 7-dependent lymphocyte aggregation, but it inhibits other α

The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 711-nm. BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors. However, the spillover can be corrected through compensation as with any other dye combination.

TRUSTED_SUSTAINABILITY

Specifications

Antigen LPAM-1
Applications Flow Cytometry
Classification Monoclonal
Clone DATK32
Concentration 0.2mg/mL
Conjugate Brilliant Violet 711
Description Itga4Itgb7; α4β7 Integrin; alpha 4 beta 7 integrin; CD49dβ7
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen AKR/Cum mouse T lymphoma line TK1
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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