TER-119/Erythroid Cells Rat anti-Mouse, Brilliant Violet 786, Clone: TER-119, BD Optibuild™
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 740875
The TER-119 antibody specifically binds to a 52 kDa molecule associated with glycophorin A on cells of the erythroid lineage in embryonic yolk sac, fetal liver, newborn liver, adult bone marrow, adult peripheral blood, and adult lymphoid organs. The TER-119 antigen is expressed on erythroid cells from pro-erythroblast through mature erythrocyte stages, but not on cells with BFU-E or CFU-E activities. The TER-119 epitope is not detected on hematopoietic stem cells, lymphoid cells, myeloid cells, or erythroleukemia lines. The TER-119 mAb is a component of the “lineage cocktail” used in studies of hematopoietic progenitors to detect, or deplete cells committed to the hematopoietic lineages.
The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).
|Brilliant Violet 786|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|IgG2b, κ, also known as Wistar (outbred) IgG2b, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Lymphocyte antigen 76; Ly76; Ly-76; TER-119; Ter119|
|Mouse Fetal Liver|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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