MilliporeSigma™ Rat anti-Nup96, Clone: 4H5,

Catalog No.	Quantity
MABE1039MI	100 μg

Catalog No. MABE1039MI Supplier MilliporeSigma™ Supplier No. MABE1039

Description

Rat Monoclonal Antibody

Specifically detects Nup96 clone: 4H5 in Mouse samples, and it is validated for Immunocytochemistry, Western Blotting

The murine gene Nup98 (Gene ID 269966; also known as AI849286, 4732457F17) encodes the 1816-amino acid nuclear pore complex protein Nup98-Nup96 (UniProt Q6PFD9), which is posttranslationally autocleaved between aa 800 and 801 to form Nup98 (aa 1-800) and Nup96 (aa 801-1816). The nuclear pore complex (NPC) acts as a passageway for nucleocytoplasmic transport. The core structure of the NPC is maintained by the Nup93-205 complex sandwiched between the supporting structures of the Nup107-160 complex on the nuclear and cytoplasmic faces of the pore. Nup96 is a component of the Nup107-160 complex, the largest subunit of the NPC. Nup96 knockout is reported to be fatal in mice and Nup96(±) mice with low levels of Nup96 display impaired immune response and are highly susceptible to viral infection.

Specifications

• Antigen: Nup96
• Applications: Immunocytochemistry, Western Blot
• Classification: Monoclonal
• Clone: 4H5
• Formulation: Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: Q6PFD9
• Gene Symbols: Nup98
• Host Species: Rat
• Immunogen: GST-tagged recombinant protein corresponding to mouse Nup96 near the N-terminus.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Epigenetics and Nuclear Function
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_001274093
• Target Species: Mouse
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG2a κ

For Research Use Only