MilliporeSigma™ Rat anti-Pax-9, Clone: 7C2 (P9C23),

Rat Monoclonal Antibody

Supplier:  MilliporeSigma™ MABE1041

Catalog No. MABE1041MI

Description

Specifically detects Pax-9 clone: 7C2 (P9C23) in Human, Mouse samples, and it is validated for Western Blotting

Paired box protein Pax-9 (UniProt P47242; also known as Paired box gene 9) is encoded by the Pax9 gene (Gene ID 18511) in murine species. Pax9 belongs to a family of nine transcription factors (Pax1-9) characterized by the presence of a DNA-binding ‘paired’-domain. Pax family transcription factors regulate the morphogenesis of a wide range of organs and are key factors for the development of mammalian sensory organs such as the eye (Pax6, Pax2), nose (Pax6), ears (Pax2, Pax8), and the endoderm-derived taste papillae (Pax9). In addition, Pax9 expression in the normal epithelium of the adult human oesophagus is reported to be either lost or significantly reduced in the majority of invasive carcinomas and epithelial dysplasias (precancerous lesions). The drop in the percentage of Pax9-positive cells in the epithelium decreases with increasing malignancy of the epithelial lesion.

Specifications

• Antigen: Pax-9
• Classification: Monoclonal
• Formulation: Purified rat monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: Pax9; Pax-9
• Immunogen: MBP-tagged recombinant protein corresponding to the C-terminal region of mouse Pax-9.
• Quantity: 100 μg
• Research Discipline: Epigenetics and Nuclear Function
• Gene ID (Entrez): NP_035171
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: 7C2 (P9C23)
• Gene Accession No.: P47242
• Host Species: Rat
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Purified

For Research Use Only