MilliporeSigma™ Rat anti-Pax-9, Clone: 7C2 (P9C23),

Catalog No.	Quantity
MABE1041MI	100 μg

Catalog No. MABE1041MI Supplier MilliporeSigma™ Supplier No. MABE1041

Description

Rat Monoclonal Antibody

Specifically detects Pax-9 clone: 7C2 (P9C23) in Human, Mouse samples, and it is validated for Western Blotting

Paired box protein Pax-9 (UniProt P47242; also known as Paired box gene 9) is encoded by the Pax9 gene (Gene ID 18511) in murine species. Pax9 belongs to a family of nine transcription factors (Pax1-9) characterized by the presence of a DNA-binding ‘paired’-domain. Pax family transcription factors regulate the morphogenesis of a wide range of organs and are key factors for the development of mammalian sensory organs such as the eye (Pax6, Pax2), nose (Pax6), ears (Pax2, Pax8), and the endoderm-derived taste papillae (Pax9). In addition, Pax9 expression in the normal epithelium of the adult human oesophagus is reported to be either lost or significantly reduced in the majority of invasive carcinomas and epithelial dysplasias (precancerous lesions). The drop in the percentage of Pax9-positive cells in the epithelium decreases with increasing malignancy of the epithelial lesion.

Specifications

• Antigen: Pax-9
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 7C2 (P9C23)
• Formulation: Purified rat monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: P47242
• Gene Symbols: Pax9; Pax-9
• Host Species: Rat
• Immunogen: MBP-tagged recombinant protein corresponding to the C-terminal region of mouse Pax-9.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Epigenetics and Nuclear Function
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_035171
• Target Species: Human, Mouse
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG1 κ

For Research Use Only