XRCC5, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of XRCC5.

Supplier:  Abnova Corporation PAB24993

Catalog No. 89-126-670

Description

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by nonhomologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq

Specifications

• Antigen: XRCC5
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of XRCC5.
• Formulation: In PBS, pH 7.2 (0.09% sodium azide)
• Gene Alias: FLJ39089/KARP-1/KARP1/KU80/KUB2/Ku86/NFIV
• Host Species: Rat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7520
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Gene: XRCC5
• Gene Symbols: XRCC5
• Immunogen: A synthetic peptide corresponding to XRCC5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: XRCC5 polyclonal antibody detects endogenous levels of XRCC5 protein.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only