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Invitrogen™ Rb Monoclonal Antibody (7E4B8)
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Catalog No. PIMA515240
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100 μL
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Catalog No. Quantity
PIMA515240 100 μL
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Catalog No. PIMA515240 Supplier Invitrogen™ Supplier No. MA515240
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Description

Mouse Monoclonal Antibody

MA5-15240 targets RB in indirect ELISA, IHC applications and shows reactivity with Human samples. The MA5-15240 immunogen is purified recombinant fragment of human RB expressed in E. Coli.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Rb
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 7E4B8
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene RB1
Gene Accession No. P06400
Gene Alias Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gene Symbols RB1
Host Species Mouse
Immunogen Purified recombinant fragment of human RB expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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